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Table 3 Low/not low model

From: An integrative method for scoring candidate genes from association studies: application to warfarin dosing

Gene

Name

P-Value

UBE3A

E6AP ubiquitin-protein ligase

5.39E-05

VKORC1

Vitamin K1 2,3-epoxide reductase subunit 1

1.16E-04

SLA2

Src-like adapter protein 2

2.11E-03

DICER1

Dicer1, Dcr-1 homolog

3.76E-03

CYP2C9

cytochrome P450, family 2, subfamily C

5.49E-03

SLC22A1

solute carrier family 22

1.12E-02

BBC3

BCL2 binding component 3

1.49E-02

F8

Procoagulant component

1.74E-02

HMOX2

heme oxygenase (decycling) 2

1.79E-02

MUTED

muted homolog

1.99E-02

VWF

coagulation factor VIII VWF

2.40E-02

HSD3B7

3-beta-HSD VII

2.56E-02

SPIN1

spindlin 1

2.58E-02

SELPLG

selectin P ligand

2.89E-02

FAM113B

family with sequence similarity 113, member B

2.92E-02

F13B

Fibrin-stabilizing factor B subunit

3.36E-02

MVP

major vault protein

3.39E-02

UGT2B7

UDP glucuronosyltransferase 2B7

3.83E-02

AKR7A2

aflatoxin beta1 aldehyde reductase

4.17E-02

SERTAD1

CDK4-binding protein p34SEI

4.96E-02

  1. Top 20 genes with candidate gene-scores that significantly distinguish between low dose patients and non-low-dose patients (p≤0.05). P-Values are result of t test between low-dose and non-low-dose distributions of gene-scores. Genes in bold are significant after correcting for multiple hypothesis testing.