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Figure 2 | BMC Bioinformatics

Figure 2

From: Mutagenesis Objective Search and Selection Tool (MOSST): an algorithm to predict structure-function related mutations in proteins

Figure 2

Example multiple alignment of seven protein amino acid sequences. Each example protein has 16, 15, 15, 14, 15, 12 and 13 amino acids, respectively. The multiple alignment has a length of 18 positions, which means that every sequence has at least 2 gaps. The calculation of the mean and variance of the property Ω is shown in detail for position 9 of the alignment (i = 9), with 6 amino acids and one gap (n = 6: 1 histidine, 3 threonines and 2 serines).

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