Histone modification profiles are predictive for tissue/cell-type specific expression of both protein-coding and microRNA genes

Table 1 The performance of CoreBoost based on features in CpG- or nonCpG-related proximal promoter and gene body region

HMV groups			Sensitivity	PPV	F-Score
	Promoter	CpG	0.579 ± 0.016	0.764 ± 0.028	0.658 ± 0.006
Set I		non-CpG	0.889 ± 0.032	0.771 ± 0.021	0.825 ± 0.007
	Body	CpG	0.594 ± 0.013	0.789 ± 0.021	0.678 ± 0.007
		non-CpG	0.876 ± 0.015	0.811 ± 0.013	0.842 ± 0.006
	Promoter	CpG	0.523 ± 0.016	0.717 ± 0.021	0.605 ± 0.010
Set II		non-CpG	0.908 ± 0.033	0.790 ± 0.021	0.844 ± 0.007
	Body	CpG	0.588 ± 0.015	0.736 ± 0.020	0.653 ± 0.008
		non-CpG	0.892 ± 0.014	0.821 ± 0.012	0.854 ± 0.006

Averages and errors are given as the mean and standard deviation from 100 replicates. All of the CoreBoost performance statistics have a p-value < 1e-5.

ISSN: 1471-2105