FunFOLD: an improved automated method for the prediction of ligand binding residues using 3D models of proteins

BMC Bioinformatics

Table 5 What is the effect on FunFOLD performance if the native structures are used for each target?

Group ID	N	Mean score for group		Mean score for FunFOLD		Increase in mean score		Mean Z-score for group		Mean Z-score for FunFOLD		P-value (raw score)		P-value (Z-score)		1 - p-value (raw score)		1 - p-value (Z-score)
		MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT	MCC	BDT
FN407	23	0.793	0.735	0.853	0.774	0.060	0.039	1.160	1.238	1.343	1.388	0.112	0.255	0.119	0.277	0.888	0.746	0.881	0.723
FN293	18	0.786	0.721	0.891	0.828	0.106	0.107	1.086	1.091	1.413	1.483	0.009	0.330	0.008	0.033	0.991	0.967	0.991	0.967
FN202	21	0.691	0.593	0.863	0.790	0.172	0.196	0.841	0.789	1.334	1.414	0.001	0.001	0.001	0.001	0.999	0.999	0.999	0.999

ISSN: 1471-2105