Table 2 Classes under negative selection compared to the genome.
From: Predicting functionally important SNP classes based on negative selection
rank | class name | p-value | q-value |
|---|---|---|---|
1 | coding | <1 × 10-8 | 1.5 × 10-3 |
2 | nonsynonymous | <1 × 10-8 | 3.1 × 10-3 |
3 | constrained elements | <1 × 10-8 | 4.7 × 10-3 |
4 | constrained elements minus coding | <1 × 10-8 | 6.3 × 10-3 |
5 | constrained elements minus genes | <1 × 10-8 | 7.8 × 10-3 |
6 | constrained elements 1 kb from genes | <1 × 10-8 | 9.4 × 10-3 |
7 | regulatory features extended | <1 × 10-8 | 1.1 × 10-2 |
8 | H3K36me3 | <1 × 10-8 | 1.3 × 10-2 |
9 | H3K79me3 | <1 × 10-8 | 1.4 × 10-2 |
10 | constrained elements 100 kb from genes | 1.0 × 10-8 | 1.6 × 10-2 |
11 | splice site | 8.0 × 10-4 | 1.7 × 10-2 |
12 | DnaseI | 4.5 × 10-3 | 1.9 × 10-2 |
13 | H3K4me3 | 5.1 × 10-3 | 2.0 × 10-2 |
14 | H3K4me2 | 8.6 × 10-3 | 2.2 × 10-2 |
15 | PolII | 1.1 × 10-2 | 2.3 × 10-2 |
16 | miRanda | 1.5 × 10-2 | 2.5 × 10-2 |
17 | cisRED | 2.4 × 10-2 | 2.7 × 10-2 |