Figure 3
From: A mutation degree model for the identification of transcriptional regulatory elements
Illustrations for mutation degree model and OCW method. (A) Illustration of the mutation degree model. The phylogenetic promoter sequences of Gene#1, Gene#2 and Gene#3 etc. are highlighted in light blue. Mutation degrees between the promoter of species1 and its phylogenetic related promoters are denoted as a1%, b1%, etc. The data in the result column is only for demonstration. The co-expressed gene set highlighted in lavender belongs to Species1. (B) Flow chart of OCW. Step 1: All oligo-nucleotides presented in co-expressed genes are enumerated; Step 2: Fisher's exact test of the over-representation significance of the enumerated oligo-nucleotides; Step 3: Calculation of the conservation score of the elements resulted from step 2, the elements with S>1 are reported; Step 4: Reporting functional elements that meet the criteria assigned by user.