Skip to main content

Table 1 The distribution of methylation proportion by patient subgroup (Group 1, Group 2), in the simulation study

From: Modeling measurement error in tumor characterization studies

 

Bernoulli

Proportion

1

Beta

distribution

2

   
  

Mean

Var

  

Scenario

(Group 1,

Group 2)

(Group 1,

Group 2)

(Group 1,

Group 2)

Difference in

Overall Means

Difference in

Overall Vars 3

a.i

(1,1)

(0.2, 0.27)

(0.01, 0.01)

0.07

0

a.ii

  

(0.04, 0.04)

0.07

0

a.iii

  

(0.01, 0.04)

0.07

0.3

b.i

 

(0.4, 0.47)

(0.01, 0.01)

0.07

0

b.ii

  

(0.04, 0.04)

0.07

0

b.iii

  

(0.01, 0.04)

0.07

0.3

c.i

(0.5,0.7)

(0.4, 0.47)

(0.01, 0.01)

0.13

0.01

c.ii

  

(0.04, 0.04)

0.13

0.01

c.iii

  

(0.01, 0.04)

0.13

0.02

  1. 1 The probability that the true methylation proportion is positive
  2. 2 Distribution of the true methylation proportion in methylated tumors
  3. 3 Estimated from the data.
Back to article page

BMC Bioinformatics

ISSN: 1471-2105

Contact us