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Table 1 Performance of CAMBa at various thresholds on the Rice and Wheat data sets

From: Statistical Mutation Calling from Sequenced Overlapping DNA Pools in TILLING Experiments

Rice

Wheat

F ( t )

Pred

Conf

FP

FN

Sens

Spec

F ( t )

Pred

Conf

FP

FN

Sens

Spec

0

308

11

233

0

100.00

98.71

-10

310

37

208

5

95.33

95.44

1

131

11

56

0

100.00

99.69

-5

172

36

73

8

92.52

98.40

2

75

10

7

7

90.67

99.96

0

107

36

8

8

92.52

99.82

3

54

10

0

21

72.00

100.00

5

92

33

1

16

85.05

99.98

4

46

9

0

29

61.33

100.00

10

81

31

0

26

75.70

100.00

5

40

7

0

35

53.33

100.00

15

59

21

1

49

54.21

99.98

  1. Performance of CAMBa at various thresholds on the Rice (left) and Wheat data sets. F(t) = CAMBa threshold, Pred = # predicted mutations at that threshold, Conf = # of the predicted mutations which overlap with the confirmed mutations (11 in rice and 39 in wheat), FP = # false positives, FN = # false negatives, Sens = Sensitivity, Spec = Specificity. We underscore the line associated with the recommended number of predictions for both Rice and Wheat. We restrict our estimate of the number of False Positives to be at least 0.