Figure 2

p -value traces - Lung cancer data. Change in p-values of ridge regression coefficients in lung cancer data with increasing shrinkage parameter. p-values are plotted on the - log scale. The three SNPs that have previously been shown to be associated with lung cancer risk, rs8034191, rs16969968 and rs402710, are shown in bold. Other SNPs are represented by dotted lines. The vertical line is at λ = 150, where the ridge estimates stabilise. a approximate p-values, b permutation test p-values.