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Table 1 Performance comparison in null simulation

From: Significance testing in ridge regression for genetic data

   

Shrinkage Parameter

   

Approximate test

Permutation test

 
   

0.1

1

10

100

0.1

1

10

100

Individuals

SNPs

Outcome

        

500

20

Continuous

0.066

0.066

0.066

0.075

0.066

0.066

0.066

0.075

  

Binary

0.021

0.021

0.041

0.067

0.027

0.027

0.033

0.052

1000

1000

Continuous

0.050

0.049

0.050

0.046

0.051

0.052

0.050

0.046

  

Binary

0.118

0.092

0.066

0.053

0.054

0.056

0.053

0.051

  1. False positive rates at the nominal significance threshold α = 0.05 in null datasets. In each scenario, results are averaged over ten replicates