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Table 3 Overall mean SP and TC scores on the full-length BAliBASE 3.0 subsets.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

MSA tools

Mean SP score

Mean TC score

MSACompro

88.846

61.313

Clustalw

74.980

37.161

DIALIGN-TX

78.48

44.10

FSA

77.878

41.688

MAFFT

81.112

46.028

MSAProbs

87.336

60.248

MUSCLE

81.496

47.151

Opal

82.030

51.789

POA

71.795

33.165

Probalign

87.161

58.528

ProbCons

85.965

55.422

T-coffee

85.728

55.239

  1. Bold denotes the highest scores. MSACompro has the highest mean SP and TC scores.
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BMC Bioinformatics

ISSN: 1471-2105

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