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Table 4 Overall mean SP and TC scores on the SABmark 1.65.

From: MSACompro: protein multiple sequence alignment using predicted secondary structure, solvent accessibility, and residue-residue contacts

MSA tools

Mean SP score

Mean TC score

MSACompro

68.85

49.07

Clustalw

52.18

31.17

DIALIGN-TX

50.49

29.66

FSA

46.03

25.73

MAFFT

51.99

31.72

MSAProbs

60.55

39.95

MUSCLE

54.99

34.35

Opal

58.28

37.84

POA

38.28

19.02

Probalign

59.96

38.66

ProbCons

59.81

38.99

T-coffee

59.49

39.08

  1. Bold denotes the highest scores. The improvement of SP and TC scores on this data set is substantial.