Figure 2

Evolutions of alternative codes with MS and tMS. Evolution of the best individual and the average quality of the population using MS and tMS as fitness with codes that reflect the canonical code translation table (model 1) and with the model of natural codon reassignments (model 2). MS is the average mean square error of the effects of possible changes in the three codon bases. tMS incorporates the quantification of mistranslation in each particular base. These curves of fitness evolution were the result of an average of 50 evolutions with different initial populations. The horizontal lines indicate the corresponding MS or tMS values of the canonical code.