A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data

BMC Bioinformatics

Table 1 GMPA Analysis Clustering and Coverage of Known Metalloproteins

Metal	Known metalloprotein subunits			Proteins Clustered	Clusters
	Total	Observed	Met GMPA significance criterion		Total	With known metalloproteins
Co	5	5	3	139	16	3
Fe	35(20)	35	19	148	15	8
Mn	0	0	0	73	7	0
Mo	2	2	1	119	10	1
Ni	12(5)	12	9	153	13	4
Pb	0	0	0	90	9	0
U	0	0	0	76	7	0
V	0	0	0	45	5	0
W	5	5	4	136	11	4
Zn	5	5	1	116	9	1

Some proteins consist of multiple subunits, the number of holoenzymes are given in parentheses. Some proteins contain multiple metals and factor into multiple rows. For full clusters, refer to supplementary material.

ISSN: 1471-2105