Figure 1

Schematic for Haplotype Assembly. (a) Strobe sequencing allows for the generation of subreeds, separated by user-defined advance lengths. The reads can be mapped to the reference to detect heterozygous sites. (b) Nodes in the SNP-Graph correspond to heterozygous sites. Edges correspond to pairs of sites that are linked by a fragment. Haplotype assembly is limited to connected components of the SNP-Graph. (c) The distance between sites is used for measuring haplotype lengths. (d) The S50, N50, and AN50 measure of haplotype assembly.