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Table 11 Performance of the proposed algorithm when p 53 is deactivated and Mdm 2 is amplified.

From: Probabilistic reconstruction of the tumor progression process in gene regulatory networks in the presence of uncertainty

p 1

# networks

# network-path pairs

# paths

result

# SSD calculations

p1 = 0.1

730

1333

4

F

38,684

p1 = 0.3

2458

3810

4

F

69,050

p1 = 0.5

3937

7208

4

S

93,650

p1 = 0.7

4096

9009

4

S

113,612

  1. Performance of the proposed algorithm when p 53 is deactivated and Mdm 2 is amplified. Several different values of β1 was used (by varying p1), and β2 was set to 0.1. The perturbation probability was assumed to be known (p = p cancer = 0.001).
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BMC Bioinformatics

ISSN: 1471-2105

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