Figure 4

Performance of Methods on Synthetic Data: Accuracy. Accuracy of classification was used to compare the performance of MIPHENO, the use of raw data followed by a CDF classifier (RAW), and a group-based metric (Z) on synthetic data from populations described in Figure 2. The percent accuracy is plotted along the y-axis while the false discovery rate (FDR) cut off is along the x-axis. Each population distribution tested is shown in a separate panel. Note that MIPHENO (pink) achieved higher classification than Z (blue) (p < 2.2e-15, Wilcoxon sign rank) and both methods outperformed Raw (green) independent of the population parameters tested.