From: β-empirical Bayes inference and model diagnosis of microarray data
t | Limma | SAM | eGG | eLNN | GaGa | EB-LNN | β-EB | |
---|---|---|---|---|---|---|---|---|
In absence of outliers | ||||||||
p 1 | - | - | - | 0.0488 | 0.0458 | 0.0494 | 0.0496 | 0.0482 |
- | - | - | (0.0010) | (0.0009) | (0.0010) | (0.0010) | (0.0013) | |
AUC | 0.9861 | 0.9861 | 0.9862 | 0.9848 | 0.9734 | 0.9879 | 0.9892 | 0.9890 |
(0.0020) | (0.0021) | (0.0020) | (0.0019) | (0.0030) | (0.0017) | (0.0015) | (0.0016) | |
pAUC | 0.1929 | 0.1934 | 0.1924 | 0.1925 | 0.1894 | 0.1940 | 0.1941 | 0.1940 |
(0.0008) | (0.0008) | (0.0008) | (0.0008) | (0.0011) | (0.0006) | (0.0007) | (0.0007) | |
In presence of 10% contaminated genes with mild outliers | ||||||||
p 1 | - | - | - | 0.0807 | 0.1053 | 0.1008 | 0.0649 | 0.0504 |
- | - | - | (0.0013) | (0.0012) | (0.0014) | (0.0013) | (0.0014) | |
AUC | 0.9649 | 0.9661 | 0.9699 | 0.9515 | 0.9396 | 0.9524 | 0.9621 | 0.9870 |
(0.0031) | (0.0030) | (0.0029) | (0.0030) | (0.0026) | (0.0052) | (0.0020) | (0.0019) | |
pAUC | 0.1826 | 0.1830 | 0.1844 | 0.1696 | 0.1577 | 0.1649 | 0.1724 | 0.1924 |
(0.0012) | (0.0012) | (0.0012) | (0.0012) | (0.0009) | (0.0008) | (0.0009) | (0.0008) | |
In presence of 10% contaminated genes with extreme outliers | ||||||||
p 1 | - | - | - | 0.0834 | 0.1076 | 0.1043 | 0.0599 | 0.0489 |
- | - | - | (0.0015) | (0.0012) | (0.0014) | (0.0013) | (0.0014) | |
AUC | 0.9692 | 0.9695 | 0.9676 | 0.9488 | 0.9333 | 0.9422 | 0.9601 | 0.9880 |
(0.0031) | (0.0031) | (0.0028) | (0.0034) | (0.0030) | (0.0064) | (0.0019) | (0.0017) | |
pAUC | 0.1842 | 0.1844 | 0.1834 | 0.1684 | 0.1542 | 0.1610 | 0.1617 | 0.1931 |
(0.0012) | (0.0012) | (0.0011) | (0.0010) | (0.0010) | (0.0009) | (0.0010) | (0.0007) | |
In presence of 20% contaminated genes with mild outliers | ||||||||
p 1 | - | - | - | 0.1275 | 0.1693 | 0.1565 | 0.0946 | 0.0521 |
- | - | - | (0.0016) | (0.0014) | (0.0016) | (0.0018) | (0.0016) | |
AUC | 0.9405 | 0.9415 | 0.9430 | 0.9147 | 0.8984 | 0.9085 | 0.9502 | 0.9850 |
(0.0041) | (0.0041) | (0.0030) | (0.0028) | (0.0025) | (0.0026) | (0.0021) | (0.0017) | |
pAUC | 0.1728 | 0.1727 | 0.1723 | 0.1409 | 0.1214 | 0.1320 | 0.1601 | 0.1904 |
(0.0014) | (0.0014) | (0.0011) | (0.0009) | (0.0007) | (0.0006) | (0.0014) | (0.0007) | |
In presence of 20% contaminated genes with extreme outliers | ||||||||
p 1 | - | - | - | 0.1260 | 0.1735 | 0.1614 | 0.0869 | 0.0502 |
- | - | - | (0.0023) | (0.0014) | (0.0015) | (0.0015) | (0.0014) | |
AUC | 0.9465 | 0.9460 | 0.9455 | 0.9112 | 0.8910 | 0.8980 | 0.9421 | 0.9869 |
(0.0040) | (0.0040) | (0.0034) | (0.0035) | (0.0034) | (0.0035) | (0.0028) | (0.0017) | |
pAUC | 0.1733 | 0.1721 | 0.1720 | 0.1391 | 0.117 | 0.1282 | 0.1539 | 0.1923 |
(0.0014) | (0.0014) | (0.0012) | (0.0012) | (0.0010) | (0.0009) | (0.0016) | (0.0008) |