Protein-protein binding site identification by enumerating the configurations

BMC Bioinformatics

Table 4 Comparisons of DoBi, metaPPI, meta-PPISP and PPI-Pred

	DoBi						metaPPI						meta-PPISP						PPI-Pred
Type	Suc^a	Acc^b	Cov^c	F^g	M ^e	V ^f	Suc	Acc	Cov	F	M	V	Suc	Acc	Cov	F	M	V	Suc	Acc	Cov	F	M	V
E-I^d	67.6	56.7	61.9	0.59	23.0	7.6	70.5	61.1	36.5	0.45	12.9	10.4	55.8	56.4	54.7	0.55	24.1	13.5	47.1	39.5	37.9	0.38	23.7	15.1
others	47.9	46.4	63.3	0.53	29.5	19.8	43.8	40.7	22.2	0.28	8.0	10.1	35.6	38.5	25.7	0.30	11.8	12.6	22.9	29.3	31.3	0.30	19.0	14.7
CAPRI	50.0	48.9	55.8	0.52	25.7	12.3	50.0	46.7	24.3	0.32	15.7	12.8	26.0	27.9	30.8	0.29	19.6	13.8	28.6	25.7	29.5	0.27	28.2	19.2
Overall	53.7	50.0	60.0	0.55	26.4	13.8	52.9	48.2	26.6	0.35	12.3	11.2	36.8	38.8	35.0	0.43	18.0	13.3	31.2	30.4	32.2	0.32	23.8	16.6

^aSuc (%) is the success rate of the corresponding method on the data set.
^bAcc (%) is the average accuracy of the corresponding method on the data set.
^cCov (%) is the average coverage of the corresponding method on the data set.
^dE-I is the type of enzyme-inhibitor.
^eM is the average of the sizes predicted by the corresponding method on the data set.
^fV is the standard deviation of the sizes predicted by the corresponding method on the data set.
^gF is the F-score of the corresponding method on the data set.

ISSN: 1471-2105