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Table 3 Frequency of covariates appearing in RIM_minP model selection among 683 DE genes detected by maxP method under threshold FDR = 15%

From: Detecting disease-associated genes with confounding variable adjustment and the impact on genomic meta-analysis: With application to major depressive disorder

 

MD1_ACC

MD2_ACC

MD3_ACC

MD1_AMY

MD3_AMY

Rank average

Age

142(5)

213 (4)

205 (4)

173 (3)

218 (3)

3.6

Alcohol

299 (2)

279 (2)

221 (3)

368 (1)

195 (4)

2.4

Antidepressant

348 (1)

119 (6)

271 (2)

346 (2)

362 (1)

2.4

pH

208 (3)

150 (4)

116 (6)

108 (6)

86 (6)

5

PMI

93 (6)

120 (5)

141 (5)

133 (5)

120 (5)

5.2

Suicide

150 (4)

325 (1)

340 (1)

149 (4)

322 (2)

2.4

  1. Rank is shown in parentheses and rank average of each covariate is calculated to indicate relative degree of frequency that a covariate impacts gene expressions and confounds with disease effect.