Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control

Table 1 Obesity related interactions.

Gene/SNP	Disease	Organism(s)
Zfp69	Candidate gene for diabetes associated with obesity	Mouse and Human
Gna14	Association study of hypertension	Human
F11r	Induces hypertension in the brain stem	Rat
Gabarapl1	Regulator of insulin dependent hepatic autophagy	Mouse
Wisp1	Association study of hypertension	Human
Fdft1	Squalene (cholesterol) biosynthesis gene	Mouse and Human
Ier2	Induced gene in insulin signalling pathways	Rat
Slc24a3	Down regulated in diet sensitive obesity	Human
Crhr1	Candidate obesity gene possibly affecting feeding behavior	Mouse and Human
Qpctl	Association study identified candidate obesity gene	Human
Vcam-1	Atherosclerotic plaque associated gene	Human
Gch1	Identified in linkage studies of maximal sedentary oxygen uptake	Human
Dlgap1	Type-2 diabetes associated gene	Human
Yy1	Type-1 diabetes associated gene	Rat
Ccl19	Adipocyte inflammation	Human
Cnr2	Obesity associated adipocyte inflammation	Mouse
Atp10a/rs3664823	Obesity associated gene	Mouse
Folr2	Up-regulated in obesity associated adipose tissue	Human

Interactions identified by the variational method with previous evidence of being associated with obesity, or obesity related phenotypes

ISSN: 1471-2105