Figure 2
From: F2C2: a fast tool for the computation of flux coupling in genome-scale metabolic networks
Visualization of the LP problems solved using different algorithms. (a) The FFCA algorithm, (b) the FFCA algorithm after applying the preprocessing procedure given in Table 1 without kernel computation (Step 7), (c) the FFCA algorithm after applying the preprocessing procedure and using the kernel of the stoichiometric matrix to identify fully coupled reactions and (d) the F2C2 algorithm given in Table 3. The dashed lines mark the boundary of the Irev, Prevand Frevregions. Colors: Black - an LP problem is solved for the corresponding (ordered) pair of reactions; Gray - the corresponding LP problem is not solved due to one (or both) reactions being eliminated from the network (a preprocessing improvement); White - corresponding LP problem does not get solved due to an algorithmic improvement.