Figure 4

Comparison of metabolite and reaction overlaps for C. acetobutylicum and C. thermocellum , and B. subtilis. Although the two Clostridium organisms are same genus, the models of these two species had significant numbers of unique metabolites (left) and reactions (right), and comparisons revealed that there was more similarity in metabolite usage with a model of B. subtilis than with each other. In part, these overlaps were driven by the explicit accounting for charged tRNA species in C. thermocellum and B. subtilis models, which was also reflected in the reaction overlaps through reactions involving these metabolites.