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Table 2 Results from modRP analysis of cocaine (C), opium (O), nicotine (N), and alcohol (A) dependence comorbidities in Combined, EA, and AA populations.

From: Convergence of genetic influences in comorbidity

COMBINED (EA & AA) Population

Four

  

Three

  

Two

   
      

CO

rs1476880*

3.30E-05

 

CONA

rs1476880

1.55E-05

CON

rs1476880*

2.26E-06

CN

rs1476880*

5.30E-06

SOD3

CONA

rs1426165

2.68E-03

CNA

rs1426165

6.87E-04

CN

rs1426165

2.97E-04

ADAMTSL3

CONA

rs1169791*

1.23E-05

CNA

rs1925156*

1.20E-05

CA

rs1938584*

3.07E-05

 
   

COA

rs1938584*

3.35E-05

ON

rs1860148*

5.61E-05

 
   

ONA

rs1385513*

1.07E-04

OA

rs726427*

3.66E-04

 
      

NA

rs2169325*

1.57E-04

 

EUROPEAN AMERICANS

Four

  

Three

  

Two

   
      

CO

rs1476880

3.32E-05

 

CONA

rs1476880

1.59E-05

CON

rs1476880*

2.23E-06

CN

rs1476880*

5.38E-06

SOD3

CONA

rs1426165

2.67E-03

CNA

rs1426165

6.87E-04

CN

rs1426165

2.97E-04

ADAMTSL3

CONA

rs1169791*

1.26E-05

CNA

rs1925156*

1.20E-05

CA

rs1938584*

3.06E-05

 
   

COA

rs1938584*

3.33E-05

ON

rs1860148*

5.61E-05

 
   

ONA

rs1385513*

1.07E-04

OA

rs726427*

3.66E-04

 
      

NA

rs2169325*

1.57E-04

 

AFRICAN AMERICANS

Four

  

Three

  

Two

   
   

CON

rs726344*

2.70E-05

CO

rs1015343*

9.50E-05

 

CONA

rs1476880

2.46E-04

CON

rs1476880

4.47E-05

CN

rs1476880

2.01E-05

SOD3

CONA

rs1426165

7.44E-05

CNA

rs1426165*

1.73E-05

CN

rs1426165*

3.62E-06

ADAMTSL3

   

COA

rs910633*

8.32E-05

CA

rs763869*

4.54E-05

 
      

ON

rs897119*

1.05E-04

 

CONA

rs795734*

5.03E-05

ONA

rs795734*

9.12E-06

OA

rs795734

7.06E-05

 
      

NA

rs795734

1.07E-04

 
  1. In each population, the 4-way (Four), 3-way (Three), and 2-way (Two) comorbidities proceed from left to right. * Indicates the most significant result for each comorbid phenotype, in each population. For reference, complete results for rs1426165 and rs1476880 are included in each population set. Bonferroni Corrected Threshold: 8.88e-006