Figure 2From: High-resolution genetic mapping with pooled sequencingGraphical model showing multi-locus dependencies. Dynamic Bayesian network used by MULTI POOL to capture the dependence between nearby loci in a pooled sequencing experiment. Allele frequencies in the pool influence the mix of observed sequencing reads at each locus. Here, the causal allele is x2 and its value is determined by sampling N individuals to create the pool from the population allele frequency p (where p≠1 2 indicates association).Back to article page