Table 2 Estimated posterior means and results for empirical simulation
From: Differential expression analysis for paired RNA-seq data
Case 1 | Case 2 | Case 3 | |
|---|---|---|---|
N | 10 | 5 | 3 |
μ 1 | -0.170 (0.037) | -0.169 (0.041) | -0.157 (0.041) |
| 3.653×10-4 | 3.604×10-4 | 3.83×10-4 |
(3×10-5) | (4.421×10-5) | (6.090×10-5) | |
| 0.984 (0.104) | 0.968 (0.115) | 0.955 (0.110) |
Î 1 | 0.151 (0.004) | 0.153 (0.005) | 0.156 (0.006) |
| 0.972 (0.006) | 0.993 (0.003) | 0.953 (0.011) |
FDR | 0.030 (0.008) | 0.046 (0.011) | 0.068 (0.013) |
| 0.024 (0.004) | 0.037 (0.005) | 0.049 (0.006) |
Sensitivity | 0.928 (0.014) | 0.866 (0.020) | 0.802 (0.025) |
Specificity | 0.995 (0.001) | 0.994 (0.002) | 0.991 (0.002) |
Case 4 | Case 5 | Case 6 | |
N | 10 | 5 | 3 |
μ 1 | 0.007 (0.035) | 0.006 (0.038) | -0.002 (0.037) |
| 3.634×10-4 | 3.532×10-4 | 3.450×10-4 |
(2.931×10-5) | (4.155×10-5) | (5.283×10-5) | |
| 1.172 (0.048) | 1.151 (0.059) | 1.140 (0.050) |
Î 1 | 0.179 (0.003) | 0.183 (0.004) | 0.188 (0.005) |
| 0.990 (0.002) | 0.979 (0.004) | 0.965 (0.007) |
FDR | 0.030 (0.008) | 0.044 (0.009) | 0.064 (0.012) |
| 0.021 (0.004) | 0.031 (0.005) | 0.042 (0.006) |
Sensitivity | 0.953 (0.011) | 0.906 (0.015) | 0.862 (0.020) |
Specificity | 0.995 (0.001) | 0.992 (0.002) | 0.989 (0.002) |