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Figure 2 | BMC Bioinformatics

Figure 2

From: Accounting for immunoprecipitation efficiencies in the statistical analysis of ChIP-seq data

Figure 2

Validation of enriched bins detected by separate and joint models, using ChromHMM. Validation of the enriched bins detected by the intersection (CBP: 5903, p300: 22984, first row) and union (CBP: 22762, p300: 43003, second row) of separate analyses of technical replicates at T30, and by the joint model proposed in this paper (CBP: 15562, p300: 32845, last row), using ChromHMM with a 4-state hidden Markov model. The left plots show heatmaps of the probabilities (in percentages) that the CBP and p300 detected bins are enriched given each identified chromatin-state. The right plots show the relative percentage of the genome represented by each chromatin state (first column) and the relative fold enrichment for several types of annotation (remaining columns).

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