TFBS | Enrichment Analysis (p-value) | RLQ | Description |
---|---|---|---|
AP-1 (C) | Â | Ă— | Activator protein 1. Signal transduction cascade mediated by glucocorticoids [30] |
AP-1 (Q6) |  | × | — |
AP-2 (Alpha) | Ă— (0.0853) | Â | Activating-protein 2. Regulatory roles in early development, apoptosis and cell-cycle control |
AP-2 (Q6) | × (0.0618) |  | — |
ATF | Â | Ă— | Activating transcription factor (class of AP-1 transcription factors dimers). |
Brachyury | Â | Ă— | Transcription factor over-expressed in numerous lung tumor. Known to mediate epithelial-mesenchymal transition and promote invasion. |
CDPCR3HD | Â | Ă— | Cut-like homeodomain protein |
c-Myb | Â | Ă— | Myb proto-oncogene protein. Regulation of cell proliferation/differentiation, regulation of human glucocorticoid receptor [34] |
CRE-BP1 | Â | Ă— | Activating transcription factor 2. <Activation of transcription by interaction with glucocorticoid response elements [33] |
CREB | Â | Ă— | cAMP response element-binding protein. |
c-Rel | Ă— (0.0009) | Ă— | Proto-oncogene c-Rel. Member of the NF- κB family. |
Freac2 | Â | Ă— | Forkhead-related activator. Differential activation of lung specific genes. Involved in cell growth/proliferation mechanisms |
Freac3 |  | × | — |
Freac4 |  | × | — |
GATA-1 | Â | Ă— | GATA-binding protein 1 (globin transcription factor 1). Involved in cell growth, cancer. |
MAZR | Ă— (0.0006) | Â | Zinc finger protein related factor. |
MZF1 (01) | Ă— (0.0012) | Â | Myeloid zinc finger protein. Control of cell proliferation. |
MZF1 (02) | × (0.0196) |  | — |
NF1 | Â | Ă— | Nuclear factor 1. Chromatin remodeling and transcriptional activation. |
NF- κB | Ă— (0.0043) |  | Nuclear factor κB. Anti-inflammatory action of steroids [31]. |
NF- κB 50 | Ă— (0.0035) |  | — |
NF- κB 65 | Ă— (<.0001) | Ă— | — |
NF- κB C | Ă— (0.0317) |  | — |
NF- κB Q6 | Ă— (0.0027) | Ă— | — |
Oct-1 | Â | Ă— | Octamer-binding transcription factor 1. |
Olf-1 | Ă— (0.0404) | Ă— | Olfactory neuron-specific factor. |
Sp1 | Ă— (0.0313) | Â | Stimulating protein 1. Ubiquitous zinc finger transcription factor. |
Spz1 | Ă— (<.0001) | Ă— | Spermatogenic leucine zipper protein 1. |
STAT | Ă— (0.0661) | Â | Signal transducer and activator of transcription. Transcription factors in cytokine-mediated biological responses. |
STAT1 | × (0.0021) |  | — |
TATA (01) | Ă— (0.0015) | Â | Cellular and viral TATA box elements. |
TATA (C) | × (0.0345) |  | — |
TAXCREB | Ă— (0.0389) | Â | Tax/CREB complex. |
Tst-1 | Ă— (0.0628) | Â | Pou domain transcription factor. |
VBP | Â | Ă— | Vitellogenin gene-binding protein. |