Figure 13

The top candidate genes predicted for Arabidopsis response to vernalization. Here, we demonstrate predictions for a plant phenotype, response to vernalization, while also demonstrating how including paralogous phenotypes may slightly enhance resolution. These predictions are drawn from phenotype data from each species in the database, with a neighborhood cutoff of k=40. Due to the large gene expansions in plants, as well as the relatively large distance of Arabidopsis from other species in our database, paralogs are often ranked together. In the first two bins, a large gene expansion is split into separate ranks by information from an Arabidopsis phenotype (which is paralogous rather than orthologous). Those ranks labeled with green text include at least one previously known vernalization response gene (that is, a gene that was already linked with vernalization response in our database).