Figure 1

A snaphsot of KUPNetViz in action. Under the network view, the KUPKB data mapping tab is displayed, where the researcher can map onto the network several gene/protein/miRNA expression datasets and apply different criteria and combinations of kidney location(s), disease(s) and data from published studies. This snapshot focuses on the down-regulation of TGFβ1 in kidney in two renal disease states, namely in acute renal allograft rejection and interstitial fibrosis and tubular atrophy, and the up-regulation of the miRNA that targets TGFβ1 in interstitial fibrosis and tubular atrophy, as derived from two published studies.