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Table 6 Classification of GO Graphs (C# denotes criterion number)

From: GRank: a middleware search engine for ranking genes by relevance to given genes

C#

GO Graph criterion

1

All KCs in the GO Graph connect to their ancestor GO term nodes by “is-a” relations only

2

All KCs in the GO Graph connect to their ancestor GO term nodes by “part-of” relations only

3

KCs in the GO Graph connect to their ancestor GO term nodes by both, “is-a” and “part-of” relations.

4

KCs are in shallow hierarchical levels in the GO Graph. We consider a hierarchical level is shallow if it is less than six

5

KCs are in deep hierarchical levels in the GO Graph

6

Some KCs are in deep hierarchical levels in the GO Graph and others are in shallow levels