From: Ontology based molecular signatures for immune cell types via gene expression analysis
B cell | Genes up regulated | Example biological process (up regulated genes) | GO ID | Genes down regulated | Example biological process (down regulated genes) | GO ID |
---|---|---|---|---|---|---|
Mature B cell | 134 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | GO:0002504 | 57 | Antigen receptor-mediated signaling pathway | GO:0050851 |
B-1a B cell | 91 | Anatomical structure development | GO:0048856 | 66 | Cellular chloride ion homeostasis | GO:0030644 |
B-1b B cell | 66 | Cellular chloride ion homeostasis | GO:0030644 | 91 | Anatomical structure development | GO:0048856 |
Fraction F mature B cell | 2 | Cellular iron ion homeostasis | GO:0006879 | 0 | Â | Â |
Germinal center B cell | 1160 | Mitotic cell cycle | GO:0000278 | 524 | Regulation of metabolic process | GO:0019222 |
Marginal zone B cell | 99 | Antigen processing and presentation, endogenous lipid antigen via MHC class Ib | GO:0048006 | 32 | Regulation of phosphate metabolic process | GO:0019220 |
B-1 B cell | 59 | Activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway | GO:0007205 | 6 | Regulation of actin polymerization or depolymerization | GO:0008064 |
Total | 1611 | Â | Â | 776 | Â | Â |