Table 2 Structure-based predictor achieves better cross validation results than the sequence-based predictor ( p -value < 0.025)

10 Fold (95% CI)

0.96

0.939

0.936

0.896

(0.957 ~ 0.962)

(0.936 ~ 0.941)

(0.932 ~ 0.940)

(0.890 ~ 0.900)

Domain (95% CI)

0.872

0.851

0.785

0.764

(0.860 ~0.882)

(0.839 ~ 0.862)

(0.765 ~ 0.805)

(0.747 ~ 0.779)

Peptide (95% CI)

0.935

0.893

0.909

0.838

(0.929 ~ 0.941)

(0.883 ~ 0.902)

(0.898 ~ 0.918)

(0.825 ~ 0.850)

Domain + Peptide (95% CI)

0.927

0.87

0.886

0.794

(0.919 ~ 0.934)

(0.862 ~ 0.877)

(0.875 ~ 0.896)

(0.783 ~ 0.804)