Figure 3

Heatmap of archetypal analysis results. A. The relation of each sample to the seven different archetypes shown as a heat map of the coefficient matrix S. Each row represents one of the archetypes and each column represents a sample. The corresponding studies are listed above the heat map. The shading indicates how much the individual archetypes contribute to each sample. A strong correlation close to 100% is black whereas a low or no correlation is white. The white dots that appear in archetype 5 indicate mucoid samples and the white dots that appear in archetype 6 indicate samples that are hypermutators. B. Phenotypic data i.e. adaptation state (early/late), mucoid/non-mucoid and hypermutability are indicated. Reference strains (PAO1 and PA14 from study 1 and 2) are categorized as “Early”, but they are distinguished with a blue color. C. The values of Explained Sample Variance (ESV) are included to show how well the samples are described by the model.