Table 3 Comparison of different methods for classifying exposed/buried residues on 392 interface TM residues of the independent test set by rASA derived from both subunit structure and complete structure (in parentheses)
From: Lipid exposure prediction enhances the inference of rotational angles of transmembrane helices
Measurements | TMexpo | MPRAP | TMX | Rhythm (membrane-coil) | Rhythm (channel) |
|---|---|---|---|---|---|
MCC | 0.14 (0.22) | 0.12 (0.25) | 0.13 (0.17) | 0.08 (−0.06) | 0.19 (0.28) |
Sensitivity | 73.11% (81.25%) | 56.29% (67.23%) | 66.17% (72.78%) | 67.72% (63.22%) | 66.10% (77.97%) |
Specificity | 48.57% (38.50%) | 64.71% (57.59%) | 55.88% (43.98%) | 45.00% (30.77%) | 64.29% (49.32%) |
Precision | 93.55% (55.91%) | 94.00% (59.50%) | 93.70% (55.04%) | 90.68% (46.61%) | 93.98% (55.42%) |
Accuracy | 70.92% (59.44%) | 57.07% (62.23%) | 65.23% (57.95%) | 65.17% (46.63%) | 65.91% (62.12%) |