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Figure 1 | BMC Bioinformatics

Figure 1

From: A scalable, knowledge-based analysis framework for genetic association studies

Figure 1

Managing the model space with a directed acyclic graph. This graph contains seven concepts (shown as boxes). All variables are mapped to the root concept v7. Smaller sets of variables are mapped to child concepts (vertices towards the bottom of the graph). A small portion of the model space is explored for the set of variables mapped to that concept (displayed in brackets). Arrows indicate the direction of graph communications, with probabilities ρ customizing the Metropolis-Hastings proposal density. For each concept, the posterior estimates are shown for main effect variables (diagonals) and pair-wise interactions (off-diagonals). Darker shades indicate higher posterior probabilities. The boxes (blue and green) within a matrix denotes the portion of the model space previously searched.

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