Figure 6From: Estimation of CpG coverage in whole methylome next-generation sequencing studiesCoverage standardization factors. The ○ represent the standardization factors calculated using the fragment size distribution obtained from the paired-end data. The ∆ represent coverage standardization factors that would be needed for the read count method and the + for the extended read count method, where in both cases we used the fragment size distribution obtained from the paired-end data for the calculations. The × sign represent estimates of the standardization factors for which we used the kernel smoother.Back to article page