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Table 2 Comparison of oligo design programs

From: BOND: Basic OligoNucleotide Design

Program

Total oligos

Bad oligos

Good oligos

Specificity (%)

Coverage(%)

Time (s)

Speed (KB/s)

ArrayOligoSelector

365,571

289,103

76,468

20.92

32.38

249,467

2.28

OligoArray

223,103

172,817

50,286

22.54

21.30

1,568,961

0.36

OligoPicker

269,971

54,715

215,256

79.73

91.16

98,343

5.77

OligoWiz

376,965

281,080

95,885

25.44

40.61

762,536

0.74

PICKY

166,126

10,697

155,429

93.56

65.83

4,745

119.64

YODA

225,332

4,190

221,142

98.14

93.66

1,577,385

0.36

BOND

236,111

0

236,111

100.00

100.00

862

658.59

  1. The specificity represents the percentage of good oligos out of the total number. The maximum number of genes that have good oligos was estimated by our evaluation program at 236,122 oligos. The coverage represents the percentage the number of good oligos represents out of this estimated maximum.