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Table 1 Identified genes are significantly involved in the functional markers of EMT

From: Inferring microRNA and transcription factor regulatory networks in heterogeneous data

Functions

Molecules

Number

p-value

Invasion

VDR, FGF8, miR-17-5p,

16

1.26E-06 - 5.4E-03

 

miR-200a-3p, miR-429, miR-7-5p

  
 

TIMP1, CDX2, ETS1, FLNA,

  
 

FOSL1, SPDEF, TNK2, YY1

  
 

ZEB1, ZEB2.

  

Migration

ESRRA, ETS1, FOSL1,

24

3.59E-09 - 7.96E-03

 

PRKD1, SNAI2, SPDEF, TIMP1,

  
 

TNK2, ABL2, CDX2, FGF8,

  
 

FLNA, GRB7, let-7a-5p, miR-16-5p,

  
 

miR-17-5p, miR-200a-3p, miR-429,

  
 

NFIC, PRAP1, PTPRU, RXRA,

  
 

SREBF1, ZEB1

  
  1. A significant number of genes identified in the inference step belong to the class of invasion and migration which are EMT functional markers. The results are generated by IPA.
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BMC Bioinformatics

ISSN: 1471-2105

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