A systems approach for analysis of high content screening assay data with topic modeling

BMC Bioinformatics

Table 3 Scores for diagnostic topics

in vitro in vivo	Time points (HCS Assay)	Topic 1	Topic 2	Topic 3
6 ^th hr. necrosis (Setting I)	1^st Hour	0.553	0.477	0.481
	6^th Hour	0.564	0.552	0.490
	24^th Hour	0.612	0.462	0.487
	48^th Hour	0.571	0.277	0.499
24 ^th hr. necrosis (Setting II)	1^st Hour	0.41	0.58	0.52
	6^th Hour	0.45	0.57	0.50
	24^th Hour	0.48	0.66	0.49
	48^th Hour	0.47	0.89	0.48
Non-necrosis drugs for 6 ^th and 24 ^th hrs (Setting III)	1^st Hour	0.521	0.450	0.502
	6^th Hour	0.459	0.404	0.513
	24^th Hour	0.398	0.371	0.522
	48^th Hour	0.439	0.187	0.520

ISSN: 1471-2105