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Table 1 Descriptive statistics of global and treatment enriched chain sets

From: Pathway-based drug repositioning using causal inference

 

Complete chain set C

Enriched chain subset C*

# of chains

2,711,440

135,936

Node set

# of drugs |D|

979

655

 

# of targets |T|

538

397

 

# of pathways |P|

207

199

 

# of genes |G|

1,122

838

 

# of diseases |S|

1,650

583

Edge set

|D×T|

2,953

2,074

 

|T×P|

2,922

2,004

 

|P×G|

2,772

2,179

 

|G×S|

6,496

3,954

# of drug-disease associations

389,945

6,268