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Figure 1 | BMC Bioinformatics

Figure 1

From: Molecular docking analysis of 2009-H1N1 and 2004-H5N1 influenza virus HLA-B*4405-restricted HA epitope candidates: implications for TCR cross-recognition and vaccine development

Figure 1

Conformational changes of DM1-TCR/HLA-B*4405/epitope complexes caused by epitope mutations. (A) Mutation K4T in the exposed region of 2004-H5N1 epitope 50 induced interaction of the C-terminal Lys8 and Leu9 with DM1-TCR. (B) Reduced exposed DM1-TCR (grey) contact area caused by mutation H5N of 2004-H5N1 epitope 412. Epitopes are shown in green (2004-H5N1) and magenta (2009-H1N1). Residue side chains are presented as lines.

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BMC Bioinformatics

ISSN: 1471-2105

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