Protein function annotation with Structurally Aligned Local Sites of Activity (SALSAs)

BMC Bioinformatics

Table 4 Local structural alignment of the predicted active site residues by SALSA for a known ECH from Rattus norvegicus (PDB ID 1ey3) with predicted residues for a Structural Genomics protein from Mycobacterium avium (PDB ID 3q1t), reported to be an ECH.

Known catalytic residues are shown in boldface. Residues predicted by POOL are in uppercase; residues not predicted are in lowercase. Note the poor match between the residues of the SG protein with those of the representative ECH.

ISSN: 1471-2105