Figure 5

Effect of the allele sampling bias on the accuracy of the most probable genotypes. The heatmap represents the observed accuracy of the most probable genotypes in simulated datasets, as a function of the allele sampling bias (λ, above each plot), the ratio between the estimated and the true allele sampling bias ($\widehat{\lambda }/\lambda$), and the frequency of the alternative allele. Each combination of real and estimated λ values is simulated 1000 times, using 500 individuals sequenced at 4 × coverage and a random allele frequency.