Table 1 Currently implemented modules
From: ISAAC - InterSpecies Analysing Application using Containers
Module | Datasource(s) | Usage |
|---|---|---|
Genome | Search for genes, transcripts and proteins and add them to sets. Features are visualized. | |
Protein Interaction | STRING [8] | Analyze protein interactions within a set. Identify interacting proteins and add them to sets. |
Pathway | KEGG [7] | Analyze genes in sets in a metabolic and pathways context. Add further genes of a pathway to sets. |
GO enrichment | GeneOntology [4] | Functional characterization of sets. Extend sets based on function. |
microRNA | TarBase [38] | Reveal microRNA based regulation of genes in sets. Search for genes regulated by specific microRNAs. |
Disease | OMIM [5] | Identify mendelian disease genes in sets. Search for genes associated with a mendelian disease. |
Drug | DrugBank [6] | Identify drug targets in sets. Search for genes affected by a drug. |
Orthology | Ensembl [2] | Orthology based translation of sets to other species. |
Team Work | - | Share sets between users and within groups. |