Figure 3
From: Variant detection sensitivity and biases in whole genome and exome sequencing
Minimum per-site mapped depth required to correctly genotype a site in matched TCGA exome and genome samples. Coding SNPs at HapMap 3.3 positions [16] with identical genotypes and alleles between matched TCGA exome and genome samples in the full alignments. a) The minimum per-site mapped depth required for a correct genotype call in TCGA-WXS and TCGA-WGS matchd samples. b) The number of extra reads required to correctly identify a SNP in the TCGA-WXS sample.