Figure 2

An example of the Luria–Delbrück program execution. The program was executed from 1 WT to 100 cells. (A) Schematic representation of the eSTG rules. (B) Typical lineage tree execution where mutations do not occur early. (C) Rare lineage tree execution where a mutation occurs early. (D) Average population size over time (calculated from 1000 stochastic executions). (E) Clone size distribution (calculated from 1000 stochastic executions). In the rare events where the mutation happens early in the lineage, the clone size of the mutated population is large.