Figure 5

Folding kinetics of the Spliced Leader RNA from L. collosoma simulated with HIKINETICS restricted to strictly negative (SN) structures. The calculation is based on all ${\pi }_h^{\mathit{\text{SN}}}$hishapes plus the open chain ([_]), which was used as the starting structure for this simulation. The simulation took 14 min using 64 cores of a 4x AMD Opteron 6282SE machine with 512 GB RAM running under openSuSE 12.2. This figure was generated using. '/HiKinetics.rb -i Input/spliced_leader.seq -o Output/spliced_leader_SN -k 100 -t 4 -s’.