Stability SCAD: a powerful approach to detect interactions in large-scale genomic study

BMC Bioinformatics

Table 7 Empirical selection probability of significant SNP pairs in Beijing study by the _S LASSO

SNP1(rs)	Gene1	SNP2(rs)	Gene2	^a Π
SNP1(rs)	Gene1	SNP2(rs)	Gene2	Beijing study _SLASSO
rs3779632	PTK2B	rs9644448	PTK2	1.000
rs2736100	TERT	rs11994882	PTK2B	0.904
rs10109684	PTK2	rs11231735	BAD	0.904
rs11994882	PTK2B	rs4983387	AKT1	0.840
rs6969923	PIK3CG	rs11997161	PTK2	0.788
rs2677764	PIK3CA	rs2821142	MUSK	0.784
rs4551415	PTK2	rs1359711	MUSK	0.740
rs1550099	CHRNG	rs10817088	MUSK	0.706
rs12466358	CHRNG	rs2565062	PTK2B	0.700
rs3791723	CHRNG	rs7839119	PTK2	0.684
rs7839119	PTK2	rs12544802	PTK2	0.628
rs9773817	PTK2B	rs6018088	SRC	0.624
rs479744	FOXO3	rs7952435	BAD	0.610
rs2736122	TERT	rs12945577	CHRNB1	0.598
rs10817082	MUSK	rs5994451	YWHAH	0.596
rs251398	PIK3R1	rs10733579	MUSK	0.530
rs3781626	RAPSN	rs6018348	SRC	0.514
rs4727666	PIK3CG	rs7856889	MUSK	0.506

^aΠ represents a predictor’s empirical probability of model inclusion under 500 times subsampling.

ISSN: 1471-2105