Table 5 Distances (Å) between the amino acid of the protease and the PI heteroatoms

PR-IDV

[2R5P]

[1K6C]

D29V

PR-LPV

[2Q5K]

[1RV7]

D29V

29/A-N₂

6.1

6.1

5.4

25/A-O₄

5.4

6.8

9.1

29/B-O₄

3.9

4.2

4.8

25/B-O₄

5.5

7.8

9.9

30/A-N₂

6.5

6.6

6.3

29/A-O₁

5.8

10.8

6

30/B-O₄

6.3

6.4

7

29/B-O₃

6

10.3

5.3

82/A-O₂

10.1

10.7

11.2

30/A-O₁

3.7

9.8

7.1

82/B-N₁

6.1

6.2

7.5

30/B-O₃

6.7

10.1

5.3

84/A-O₂

8.3

8.2

9.3

84/A-O₄

8.2

10.1

10.4

84/B-N₁

7.9

7.9

8.4

84/B-O₃

7.6

8.1

8.2

PR-SQV

[3OXC]

[3CYW]

D29V

PR-RTV

[3NDX]

[1RL8]

D29V

29/A-O_D1

4.1

5.3

3.5

29/A-O₇₆

4

3.8

4.9

29/B-N₃

6.1

6

7.5

29/B-N₅

5.6

4

5.1

30/A-O_D1

3.8

4.2

3.8

30/A-O₇₆

6.1

6.1

6.9

30/B-N₃

6.5

6.4

7.5

30/B-S₃

4

5.5

8.8

48/A-N_D2

3.4

5.6

7.9

82/A-N₁₁

9.4

9.5

9.6

48/B-N₃

4

6.3

6.3

82/B-O₇

10.5

10.3

11.6

PR-APV

[3NU3]

[3NU4]

D29V

PR-DRV

[IT3R]

[2HS1]

D29V

29/A-O₆

4.5

4.2

4

29/A-O₂₆

3.9

4.1

10.4

29/B-N₃

4.3

4.6

7.6

29/B-N₁

4.6

4.4

7.3

30/A-O₆

4.5

3.8

3.8

30/A-O₂₆

3.8

3.8

12.3

30/B-N₃

3.3

3.7

10.7

30/B-N₁

3.8

3.7

9.5

32/A-O₆

6.6

6.6

6.9

32/A-O₂₆

7.2

7.5

13.9

32/B-N₃

6.3

6.3

15

32/B-N₁

6.1

7.6

13.3

PR-TPV

[2O4P]

[1DS4]

D29V

PR-ATV

[3EKY]

[3OXX]

D29V

29/A-N₂₈

6.1

6.2

9.6

29/A-O_AI

3.9

5.1

5.6

29/B-O₁

9.1

9.4

8.4

29/B-O_AJ

3.9

4

8.3

30/A-N₂₈

6.2

6

8.7

30/A-O_AI

6.1

6

8.7

30/B-O₁

10

10.2

8.6

30/B-O_AJ

6

6

8.5

82/A-O₈

10.7

10

10.2

50/A-O₁

5.7

5.6

4.8

82/B-O₇

10.3

9.9

7.7

50/B-O₁

5.3

5.4

3.6

84/A-O₈

8.3

8.1

8.5

84/B-O₈

8.4

7.8

8.1

PR-NFV

[3EKX]

[2PYM]

D29V

29/A-N₁₂

5.9

6.3

5.8

29/B-O₃₈

5

4.4

3.8

30/A-N₁₂

6.4

6.7

6.3

30/B-O₃₈

3.9

3.7

3.7